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- $Unique_ID{BRK01019}
- $Pretitle{}
- $Title{How Can One Develop an Allergic Reaction to Penicillin?}
- $Subject{allergy penicillin allergic reaction allergies penicillins allergen
- medicine medicines medication medications}
- $Volume{R-0}
- $Log{
- The Process of an Allergic Reaction*0001201.scf
- Allergen Injection Desensitization*0001303.scf}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
-
-
- How Can One Develop an Allergic Reaction to Penicillin?
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-
- QUESTION: A close member of our family recently had a frightening experience
- as he developed an allergic reaction to an injection of penicillin. We
- wondered how that could happen when he was never allergic before. Does it
- mean he will have another problem if he ever takes penicillin again? Do any
- other members of the family have to worry about the chance that they might
- also be allergic to this medicine?
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-
- ANSWER: Although the exact number of cases of allergic reactions to
- penicillin are not known, estimates place it at from 1 percent to as many as
- 10 percent of all people treated. While most of the reactions take the form
- of skin rashes and hives, they can be so severe as to cause the death of the
- patient. Though there are many hundreds of different medications used to
- treat disease and illness in the United States, penicillin is the most common
- drug causing allergic reactions. Perhaps 400 to 800 deaths per year may be
- due to these reactions, and 75 percent occur in people who had no history of a
- previous problem. There is no evidence of family tendency to these allergic
- reactions, so you and the other members of your family have nothing special to
- fear. The sensitivity to penicillin develops most frequently when penicillin
- has been used in ointments or creams, or when treatment with this antibiotic
- has been given for many short periods of time. It usually happens in adults
- between the ages of 20 and 40, but can develop in people of all ages. While a
- reaction may occur even when the medication is taken by mouth, it is more
- severe and happens most frequently when it has been given by injection. When
- the history is uncertain but the possibility of an allergy does exist,
- physicians may either use another antibiotic with a similar action, or in the
- cases where only penicillin will do, perform a skin test to detect the
- possibility that an allergy exists. There are several methods used to reduce
- the patient's sensitivity to penicillin by starting with very small doses
- initially, then gradually doubling the amount until the full dose needed can
- be given safely. My advice would be that this family member stay away from
- penicillin and obtain a Medic-Alert bracelet to prevent the chance of ever
- receiving this medication while unable to give a history.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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-